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Gene: P2ry2 (purinergic receptor P2Y2) Rattus norvegicus
Symbol: P2ry2
Name: purinergic receptor P2Y2
CRRD ID: 62088
Description: Exhibits A1 adenosine receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Involved in several processes, including positive regulation of penile erection; positive regulation of prostaglandin secretion; and regulation of cytosolic calcium ion concentration. Localizes to apical plasma membrane; basolateral plasma membrane; and glutamatergic synapse. Colocalizes with early endosome; lysosome; and mitochondrion. Used to study impotence. Orthologous to human P2RY2 (purinergic receptor P2Y2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: ATP receptor; P2U purinoceptor 1; P2U1; P2Y ATP receptor 2; P2Y purinoceptor 2; P2Y2; purinergic receptor P2Y, G-protein coupled 2; purinergic receptor P2Y, G-protein coupled, 2
Homo sapiens (human) : P2RY2 (purinergic receptor P2Y2)  HGNC  Alliance
Mus musculus (house mouse) : P2ry2 (purinergic receptor P2Y, G-protein coupled 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : P2ry2 (purinergic receptor P2Y2)
Pan paniscus (bonobo/pygmy chimpanzee) : P2RY2 (purinergic receptor P2Y2)
Canis lupus familiaris (dog) : P2RY2 (purinergic receptor P2Y2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P2ry2 (purinergic receptor P2Y2)
Sus scrofa (pig) : P2RY2 (purinergic receptor P2Y2)
Chlorocebus sabaeus (African green monkey) : P2RY2 (purinergic receptor P2Y2)
Heterocephalus glaber (naked mole-rat) : P2ry2 (purinergic receptor P2Y2)
more info ...
Allele / Splice: P2ry2em6Mcwi   P2ry2em7Mcwi  
Genetic Models: SS-P2ry2em7Mcwi SS-P2ry2em6Mcwi
Is Marker For: Strains:   SD-Tg(Ubc-P2ry2)Besey  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01166,031,228 - 166,045,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,031,272 - 166,037,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01172,227,726 - 172,241,921 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41158,440,018 - 158,454,213 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11158,519,034 - 158,533,227 (-)NCBI
Celera1153,434,723 - 153,448,921 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on P2ry2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62088
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.