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Gene: Mpc1 (mitochondrial pyruvate carrier 1) Rattus norvegicus
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Symbol: Mpc1
Name: mitochondrial pyruvate carrier 1
Description: Predicted to have pyruvate transmembrane transporter activity. Predicted to be involved in cellular response to leukemia inhibitory factor; mitochondrial acetyl-CoA biosynthetic process from pyruvate; and mitochondrial pyruvate transmembrane transport. Predicted to localize to the integral component of mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial pyruvate carrier deficiency. Orthologous to human MPC1 (mitochondrial pyruvate carrier 1); PARTICIPATES IN citric acid cycle pathway; fructose-1,6-bisphosphatase deficiency pathway; fumaric aciduria pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: apoptosis-regulating basic protein; brain protein 44-like; Brp44l; SLC54A1; solute carrier family 54 member 1
Orthologs:
Homo sapiens (human) : MPC1 (mitochondrial pyruvate carrier 1)  HGNC  Alliance
Mus musculus (house mouse) : Mpc1 (mitochondrial pyruvate carrier 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpc1 (mitochondrial pyruvate carrier 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MPC1 (mitochondrial pyruvate carrier 1)
Canis lupus familiaris (dog) : MPC1 (mitochondrial pyruvate carrier 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpc1 (mitochondrial pyruvate carrier 1)
Sus scrofa (pig) : MPC1 (mitochondrial pyruvate carrier 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0153,026,608 - 53,038,229 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0154,275,046 - 54,286,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4147,077,723 - 47,089,344 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1147,080,667 - 47,092,289 (-)NCBI
Celera148,200,723 - 48,212,344 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mpc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620902
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.