Gene: Fbn1 (fibrillin 1) Rattus norvegicus
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Symbol: Fbn1
Name: fibrillin 1
Description: Predicted to have several functions, including calcium ion binding activity, extracellular matrix structural constituent, and heparin binding activity; involved in cellular response to insulin-like growth factor stimulus, cellular response to transforming growth factor beta stimulus, and metanephros development; localizes to the collagen-containing extracellular matrix; biomarker of glomerulonephritis, hypertension, liver cirrhosis, mesangial proliferative glomerulonephritis, and type 2 diabetes mellitus; orthologous to human FBN1 (fibrillin 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: fibrillin-1
Orthologs:
Homo sapiens (human) : FBN1 (fibrillin 1)  HGNC  Alliance
Mus musculus (house mouse) : Fbn1 (fibrillin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbn1 (fibrillin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FBN1 (fibrillin 1)
Canis lupus familiaris (dog) : FBN1 (fibrillin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbn1 (fibrillin 1)
Sus scrofa (pig) : FBN1 (fibrillin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03117,569,708 - 117,766,160 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03124,094,458 - 124,290,346 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43112,608,480 - 112,804,118 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13112,514,052 - 112,709,691 (-)NCBI
Celera3111,411,207 - 111,605,886 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences