Gene: Casp7 (caspase 7) Rattus norvegicus
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Symbol: Casp7
Name: caspase 7
Description: Exhibits cysteine-type peptidase activity; involved in several processes, including aging, leukocyte apoptotic process, and proteolysis; localizes to the cytosol and intracellular membrane-bounded organelle; biomarker of several diseases, including acute myocardial infarction, endometritis, sciatic neuropathy, transient cerebral ischemia, and type 2 diabetes mellitus; orthologous to human CASP7 (caspase 7); PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; glutathione metabolic pathway; INTERACTS WITH (RS)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: caspase-7
Orthologs:
Homo sapiens (human) : CASP7 (caspase 7)  HGNC  Alliance
Mus musculus (house mouse) : Casp7 (caspase 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp7 (caspase 7)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP7 (caspase 7)
Canis lupus familiaris (dog) : CASP7 (caspase 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp7 (caspase 7)
Sus scrofa (pig) : CASP7 (caspase 7)
more info ...
Allele / Splice: Casp7Tn(sb-T2/Bart3)2.280Mcwi  
Genetic Models: F344-Casp7Tn(sb-T2/Bart3)2.280Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01277,190,557 - 277,242,779 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01284,572,208 - 284,623,736 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41262,689,300 - 262,721,591 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11262,900,344 - 262,932,633 (+)NCBI
Celera1251,144,026 - 251,176,065 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620944
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.