Gene: Eif2s1 (eukaryotic translation initiation factor 2 subunit alpha) Rattus norvegicus
Analyze
Symbol: Eif2s1
Name: eukaryotic translation initiation factor 2 subunit alpha
Description: Predicted to have ribosome binding activity and translation initiation factor activity; involved in several processes, including aging, cellular response to heat, and positive regulation of cell death; localizes to the cytoplasm, glial limiting end-foot, and nucleus; used to study middle cerebral artery infarction; biomarker of transient cerebral ischemia; orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha); PARTICIPATES IN translation initiation pathway; Endoplasmic Reticulum-associated degradation pathway; hepatitis C pathway; INTERACTS WITH (R)-lipoic acid; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eIF-2-alpha; EIF-2A; EIF-2alpha; eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 (alpha ); eukaryotic translation initiation factor 2, subunit 1 alpha; MGC93488
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06102,048,372 - 102,073,041 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06111,422,397 - 111,447,066 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46101,495,444 - 101,520,113 (+)NCBIRGSC3.4rn4RGSC3.4
Celera696,060,793 - 96,085,462 (+)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Eif2s1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620963
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.