Gene: Prkcq (protein kinase C, theta) Rattus norvegicus
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Symbol: Prkcq
Name: protein kinase C, theta
Description: Exhibits protein serine/threonine kinase activity; involved in several processes, including aging, positive regulation of cellular component organization, and positive regulation of transport; localizes to several cellular components, including the cytoplasm, neuromuscular junction, and nucleus; biomarker of hyperinsulinism and prostate adenocarcinoma; orthologous to human PRKCQ (protein kinase C theta); PARTICIPATES IN eicosanoid signaling pathway; endothelin signaling pathway; insulin signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: nPKC-theta; Pkcq; protein kinase C theta type
Orthologs:
Homo sapiens (human) : PRKCQ (protein kinase C theta)  HGNC  Alliance
Mus musculus (house mouse) : Prkcq (protein kinase C, theta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcq (protein kinase C theta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCQ (protein kinase C theta)
Canis lupus familiaris (dog) : PRKCQ (protein kinase C theta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcq (protein kinase C theta)
Sus scrofa (pig) : PRKCQ (protein kinase C theta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01770,971,915 - 71,105,286 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01772,669,688 - 72,800,895 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41778,486,998 - 78,566,741 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11778,497,951 - 78,520,090 (-)NCBI
Celera1766,745,895 - 66,876,546 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkcq
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620968
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.