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Gene: Pros1 (protein S) Rattus norvegicus
Symbol: Pros1
Name: protein S
Description: Predicted to have calcium ion binding activity. Involved in several processes, including liver development; positive regulation of phagocytosis; and response to lipopolysaccharide. Localizes to extracellular space and protein-containing complex. Human ortholog(s) of this gene implicated in cerebral infarction; protein S deficiency; and thrombophilia. Orthologous to human PROS1 (protein S); PARTICIPATES IN protein C anticoagulant pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Pros; protein S (alpha); vitamin K-dependent protein S
Homo sapiens (human) : PROS1 (protein S)  HGNC  Alliance
Mus musculus (house mouse) : Pros1 (protein S (alpha))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pros1 (protein S)
Pan paniscus (bonobo/pygmy chimpanzee) : PROS1 (protein S)
Canis lupus familiaris (dog) : PROS1 (protein S)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pros1 (protein S)
Sus scrofa (pig) : PROS1 (protein S)
Chlorocebus sabaeus (African green monkey) : PROS1 (protein S)
Heterocephalus glaber (naked mole-rat) : Pros1 (protein S)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.071,206,648 - 1,288,140 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl71,206,648 - 1,288,134 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.071,199,864 - 1,279,998 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera13237,157 - 317,730 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pros1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 620971
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.