Gene: Dab2 (DAB adaptor protein 2) Rattus norvegicus
Analyze
Symbol: Dab2
Name: DAB adaptor protein 2
Description: Predicted to have several functions, including AP-2 adaptor complex binding activity, SMAD binding activity, and clathrin adaptor activity; involved in several processes, including cellular response to growth factor stimulus, negative regulation of signal transduction, and positive regulation of cellular component organization; localizes to the clathrin-coated vesicle membrane, perinuclear region of cytoplasm, and plasma membrane; used to study myocardial infarction; biomarker of metabolic acidosis and myocardial infarction; orthologous to human DAB2 (DAB adaptor protein 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adaptor molecule disabled-2; C9; DAB2, clathrin adaptor protein; differentially expressed in ovarian carcinoma 2; disabled 2, mitogen-responsive phosphoprotein; disabled homolog 2; disabled homolog 2 (Drosophila); disabled homolog 2 mitogen-responsive phosphoprotein; disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila); Doc-2; DOC-2 p82 isoform; Doc2; mitogen-responsive phosphoprotein
Orthologs:
Homo sapiens (human) : DAB2 (DAB adaptor protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Dab2 (disabled 2, mitogen-responsive phosphoprotein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dab2 (DAB adaptor protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DAB2 (DAB adaptor protein 2)
Canis lupus familiaris (dog) : DAB2 (DAB2, clathrin adaptor protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dab2 (DAB adaptor protein 2)
Sus scrofa (pig) : DAB2 (DAB adaptor protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0255,747,353 - 55,768,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0275,489,435 - 75,510,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,714,874 - 55,736,370 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1255,643,109 - 55,664,600 (+)NCBI
Celera251,166,390 - 51,187,877 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dab2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621007
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.