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Gene: Lamc2 (laminin subunit gamma 2) Rattus norvegicus
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Symbol: Lamc2
Name: laminin subunit gamma 2
Description: Predicted to have heparin binding activity. Predicted to be involved in several processes, including positive regulation of cell migration; positive regulation of cell population proliferation; and substrate adhesion-dependent cell spreading. Localizes to several cellular components, including the cell cortex; laminin-2 complex; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Orthologous to human LAMC2 (laminin subunit gamma 2); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; small cell lung carcinoma pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: lamimin, gamma 2; laminin subunit gamma-2; laminin, gamma 2; LOC289096
Orthologs:
Homo sapiens (human) : LAMC2 (laminin subunit gamma 2)  HGNC  Alliance
Mus musculus (house mouse) : Lamc2 (laminin, gamma 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lamc2 (laminin subunit gamma 2)
Pan paniscus (bonobo/pygmy chimpanzee) : LAMC2 (laminin subunit gamma 2)
Canis lupus familiaris (dog) : LAMC2 (laminin subunit gamma 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lamc2 (laminin subunit gamma 2)
Sus scrofa (pig) : LAMC2 (laminin subunit gamma 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01370,566,643 - 70,632,126 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01375,532,726 - 75,598,249 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41368,151,074 - 68,211,117 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11368,192,400 - 68,195,295 (-)NCBI
Celera1365,189,676 - 65,249,215 (-)NCBICelera
Cytogenetic Map13q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lamc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621053
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.