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Gene: Cdk12 (cyclin-dependent kinase 12) Rattus norvegicus
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Symbol: Cdk12
Name: cyclin-dependent kinase 12
Description: Exhibits cyclin binding activity. Involved in RNA splicing and regulation of RNA splicing. Localizes to the nuclear cyclin-dependent protein kinase holoenzyme complex and nuclear speck. Orthologous to human CDK12 (cyclin dependent kinase 12); PARTICIPATES IN RNA polymerase II transcription pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDC2-related kinase 7; Cdc2-related kinase, arginine/serine-rich; CDC2-related protein kinase 7; cell division cycle 2-related protein kinase 7; cell division protein kinase 12; Crk7; CrkRS; cyclin-dependent kinase 12 isoform; Pksc; protein kinase for splicing component; similar to human CrkRS: CDC2-related protein kinase 7
Orthologs:
Homo sapiens (human) : CDK12 (cyclin dependent kinase 12)  HGNC  Alliance
Mus musculus (house mouse) : Cdk12 (cyclin-dependent kinase 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk12 (cyclin dependent kinase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK12 (cyclin dependent kinase 12)
Canis lupus familiaris (dog) : CDK12 (cyclin dependent kinase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk12 (cyclin dependent kinase 12)
Sus scrofa (pig) : CDK12 (cyclin dependent kinase 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,157,186 - 86,210,657 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01085,953,855 - 86,019,907 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,972,428 - 87,027,794 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11086,986,797 - 87,036,966 (+)NCBI
Celera1081,950,642 - 82,003,549 (+)NCBICelera
Cytogenetic Map10q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cdk12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621111
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.