Gene: Tob1 (transducer of ErbB-2.1) Rattus norvegicus
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Symbol: Tob1
Name: transducer of ErbB-2.1
Description: Predicted to have SMAD binding activity, receptor tyrosine kinase binding activity, and transcription corepressor activity; predicted to be involved in several processes, including negative regulation of cell population proliferation, negative regulation of osteoblast differentiation, and regulation of gene expression; predicted to localize to the CCR4-NOT complex, cytoplasm, and nucleus; orthologous to human TOB1 (transducer of ERBB2, 1); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: transducer of ERBB2, 1
Orthologs:
Homo sapiens (human) : TOB1 (transducer of ERBB2, 1)  HGNC  Alliance
Mus musculus (house mouse) : Tob1 (transducer of ErbB-2.1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tob1 (transducer of ERBB2, 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TOB1 (transducer of ERBB2, 1)
Canis lupus familiaris (dog) : TOB1 (transducer of ERBB2, 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tob1 (transducer of ERBB2, 1)
Sus scrofa (pig) : TOB1 (transducer of ERBB2, 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01081,913,689 - 81,915,727 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01081,746,516 - 81,748,554 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41082,852,405 - 82,854,443 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11082,866,780 - 82,868,808 (+)NCBI
Celera1077,952,276 - 77,954,314 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tob1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621126
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.