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Gene: Rnpep (arginyl aminopeptidase) Rattus norvegicus
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Symbol: Rnpep
Name: arginyl aminopeptidase
Description: Exhibits metalloaminopeptidase activity; peptide binding activity; and transition metal ion binding activity. Involved in several processes, including aging; negative regulation of blood pressure; and retina development in camera-type eye. Localizes to several cellular components, including the cytoplasm; external side of plasma membrane; and extracellular space. Used to study hypertension. Biomarker of hypertension. Orthologous to human RNPEP (arginyl aminopeptidase); PARTICIPATES IN angiotensin IV signaling pathway; renin-angiotensin cascade pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: aminopeptidase B; AP-B; arginine aminopeptidase; arginyl aminopeptidase (aminopeptidase B); cytosol aminopeptidase IV
Orthologs:
Homo sapiens (human) : RNPEP (arginyl aminopeptidase)  HGNC  Alliance
Mus musculus (house mouse) : Rnpep (arginyl aminopeptidase (aminopeptidase B))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnpep (arginyl aminopeptidase)
Pan paniscus (bonobo/pygmy chimpanzee) : RNPEP (arginyl aminopeptidase)
Canis lupus familiaris (dog) : RNPEP (arginyl aminopeptidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnpep (arginyl aminopeptidase)
Sus scrofa (pig) : RNPEP (arginyl aminopeptidase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01352,092,863 - 52,124,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01357,144,697 - 57,163,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41348,267,923 - 48,286,295 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11348,281,967 - 48,300,338 (-)NCBI
Celera1347,022,135 - 47,040,506 (-)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Rnpep
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621137
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.