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Gene: Slc22a4 (solute carrier family 22 member 4) Rattus norvegicus
Symbol: Slc22a4
Name: solute carrier family 22 member 4
Description: Exhibits quaternary ammonium group transmembrane transporter activity. Involved in quaternary ammonium group transport. Predicted to localize to apical plasma membrane and mitochondrion. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human SLC22A4 (solute carrier family 22 member 4); PARTICIPATES IN cisplatin response pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; acrylamide.
Type: protein-coding
Also known as: Octn1; organic cation transporter OCTN1; organic cation/carnitine transporter 1; solute carrier family 22 (organic cation transporter), member 4; solute carrier family 22 (organic cation/zwitterion transporter), member 4
Homo sapiens (human) : SLC22A4 (solute carrier family 22 member 4)  HGNC  Alliance
Mus musculus (house mouse) : Slc22a4 (solute carrier family 22 (organic cation transporter), member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a4 (solute carrier family 22 member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A4 (solute carrier family 22 member 4)
Canis lupus familiaris (dog) : SLC22A4 (solute carrier family 22 member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a4 (solute carrier family 22 member 4)
Sus scrofa (pig) : SLC22A4 (solute carrier family 22 member 4)
Chlorocebus sabaeus (African green monkey) : SLC22A4 (solute carrier family 22 member 4)
Heterocephalus glaber (naked mole-rat) : Slc22a4 (solute carrier family 22 member 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01039,334,972 - 39,373,508 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01039,121,490 - 39,154,295 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1037,476,326 - 37,522,094 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc22a4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621149
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.