Gene: Il1rn (interleukin 1 receptor antagonist) Rattus norvegicus
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Symbol: Il1rn
Name: interleukin 1 receptor antagonist
Description: Exhibits interleukin-1 receptor binding activity; involved in several processes, including carboxylic acid metabolic process, cellular response to norepinephrine stimulus, and chronic inflammatory response to antigenic stimulus; localizes to the extracellular space; used to study adult respiratory distress syndrome, anti-basement membrane glomerulonephritis, hypertension, silicosis, and transient cerebral ischemia; biomarker of encephalitis and pneumonia; orthologous to human IL1RN (interleukin 1 receptor antagonist); PARTICIPATES IN interleukin-1 signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-nicotine; 15-deoxy-Delta(12,14)-prostaglandin J2.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IL-1ra; IL-1RN; IL1 inhibitor; interleukin 1 receptor antagonist gene; interleukin-1 receptor antagonist protein; IRAP
Orthologs:
Homo sapiens (human) : IL1RN (interleukin 1 receptor antagonist)  HGNC  Alliance
Mus musculus (house mouse) : Il1rn (interleukin 1 receptor antagonist)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il1rn (interleukin 1 receptor antagonist)
Pan paniscus (bonobo/pygmy chimpanzee) : IL1RN (interleukin 1 receptor antagonist)
Canis lupus familiaris (dog) : IL1RN (interleukin 1 receptor antagonist)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1rn (interleukin 1 receptor antagonist)
Sus scrofa (pig) : IL1RN (interleukin 1 receptor antagonist)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.031,449,778 - 1,468,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.031,445,598 - 1,461,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.432,607,800 - 2,613,216 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.132,607,803 - 2,611,842 (+)NCBI
Celera31,959,290 - 1,964,693 (+)NCBICelera
Cytogenetic Map3p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Il1rn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621159
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.