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Gene: Chkb (choline kinase beta) Mus musculus
Symbol: Chkb
Name: choline kinase beta
Description: Exhibits choline kinase activity. Involved in muscle organ development and phosphatidylcholine biosynthetic process. Is expressed in several structures, including alimentary system; central nervous system; cranium; heart; and sensory organ. Used to study megaconial type congenital muscular dystrophy. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; benzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Chetk; Chkl; choline kinase-like; choline/ethanolamine kinase; choline/ethanolamine kinase beta; choline/ethanolamine kinase-b; choline/ethanolaminekinase; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; ethanolamine kinase
Homo sapiens (human) : CHKB (choline kinase beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Chkb (choline kinase beta)  Alliance
Sus scrofa (pig) : CHKB (choline kinase beta)
Chlorocebus sabaeus (African green monkey) : CHKB (choline kinase beta)
Heterocephalus glaber (naked mole-rat) : Chkb (choline kinase beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1589,426,360 - 89,429,908 (-)EnsemblGRCm38mm10GRCm38
GRCm381589,426,349 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371589,256,798 - 89,260,330 (-)NCBIGRCm37mm9NCBIm37
MGSCv361589,254,134 - 89,257,666 (-)NCBImm8
Celera1591,555,430 - 91,558,962 (-)NCBICelera
Cytogenetic Map15E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Chkb
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62117
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.