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Gene: Chkb (choline kinase beta) Mus musculus
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Symbol: Chkb
Name: choline kinase beta
Description: Exhibits choline kinase activity. Involved in muscle organ development and phosphatidylcholine biosynthetic process. Is expressed in several structures, including alimentary system; central nervous system; cranium; heart; and sensory organ. Used to study megaconial type congenital muscular dystrophy. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta); PARTICIPATES IN glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid; benzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Chetk; Chkl; choline kinase-like; choline/ethanolamine kinase; choline/ethanolamine kinase beta; choline/ethanolamine kinase-b; choline/ethanolaminekinase; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; ethanolamine kinase
Orthologs:
Homo sapiens (human) : CHKB (choline kinase beta)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Chkb (choline kinase beta)  Alliance
Sus scrofa (pig) : CHKB (choline kinase beta)
Chlorocebus sabaeus (African green monkey) : CHKB (choline kinase beta)
Heterocephalus glaber (naked mole-rat) : Chkb (choline kinase beta)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1589,426,360 - 89,429,908 (-)EnsemblGRCm38mm10GRCm38
GRCm381589,426,349 - 89,429,927 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371589,256,798 - 89,260,330 (-)NCBIGRCm37mm9NCBIm37
MGSCv361589,254,134 - 89,257,666 (-)NCBImm8
Celera1591,555,430 - 91,558,962 (-)NCBICelera
Cytogenetic Map15E3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Chkb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 62117
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.