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Gene: Megf8 (multiple EGF-like-domains 8) Rattus norvegicus
Symbol: Megf8
Name: multiple EGF-like-domains 8
Description: Predicted to have calcium ion binding activity. Predicted to be involved in several processes, including embryonic morphogenesis; generation of neurons; and heart development. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Carpenter syndrome. Orthologous to human MEGF8 (multiple EGF like domains 8); INTERACTS WITH ammonium chloride; beta-naphthoflavone; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; Egfl4; epidermal growth factor-like protein 4; multiple EGF-like domain protein 4; multiple EGF-like domains protein 8; multiple epidermal growth factor-like domains 8; multiple epidermal growth factor-like domains protein 8
Homo sapiens (human) : MEGF8 (multiple EGF like domains 8)  HGNC  Alliance
Mus musculus (house mouse) : Megf8 (multiple EGF-like-domains 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Megf8 (multiple EGF like domains 8)
Pan paniscus (bonobo/pygmy chimpanzee) : MEGF8 (multiple EGF like domains 8)
Canis lupus familiaris (dog) : MEGF8 (multiple EGF like domains 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Megf8 (multiple EGF like domains 8)
Sus scrofa (pig) : MEGF8 (multiple EGF like domains 8)
Chlorocebus sabaeus (African green monkey) : MEGF8 (multiple EGF like domains 8)
Heterocephalus glaber (naked mole-rat) : Megf8 (multiple EGF like domains 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0182,184,671 - 82,234,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl182,185,034 - 82,234,045 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,448,862 - 83,497,902 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,591,805 - 80,641,334 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1180,705,607 - 80,719,439 (+)NCBI
Celera175,345,442 - 75,394,666 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Megf8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621190
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.