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Gene: Acaca (acetyl-CoA carboxylase alpha) Rattus norvegicus
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Symbol: Acaca
Name: acetyl-CoA carboxylase alpha
Description: Exhibits acetyl-CoA carboxylase activity; biotin binding activity; and kinase binding activity. Involved in fatty acid biosynthetic process; response to drug; and response to organic cyclic compound. Predicted to localize to the actin cytoskeleton; cytosol; and fibrillar center. Used to study fatty liver disease. Orthologous to human ACACA (acetyl-CoA carboxylase alpha); PARTICIPATES IN fatty acid biosynthetic pathway; Leigh disease pathway; malonic aciduria pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Acac; ACC-alpha; ACC1; acetyl-CoA carboxylase 1; acetyl-coenzyme A carboxylase; acetyl-Coenzyme A carboxylase alpha
Orthologs:
Homo sapiens (human) : ACACA (acetyl-CoA carboxylase alpha)  HGNC  Alliance
Mus musculus (house mouse) : Acaca (acetyl-Coenzyme A carboxylase alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acaca (acetyl-CoA carboxylase alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : ACACA (acetyl-CoA carboxylase alpha)
Canis lupus familiaris (dog) : ACACA (acetyl-CoA carboxylase alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acaca (acetyl-CoA carboxylase alpha)
Sus scrofa (pig) : ACACA (acetyl-CoA carboxylase alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01071,519,392 - 71,719,910 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01071,431,885 - 71,630,271 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41072,483,772 - 72,677,134 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11072,498,141 - 72,691,504 (+)NCBI
Celera1068,011,070 - 68,201,435 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Acaca
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621248
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.