Gene: Mt3 (metallothionein 3) Rattus norvegicus
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Symbol: Mt3
Name: metallothionein 3
Description: Exhibits copper ion binding activity and zinc ion binding activity; involved in brain development, negative regulation of hydrogen peroxide catabolic process, and negative regulation of neuron death; localizes to several cellular components, including the astrocyte end-foot, intracellular organelle, and neuron projection; used to study motor neuron disease; biomarker of borna disease, cerebrovascular disease (multiple), hypothyroidism, median neuropathy, and visual epilepsy; orthologous to human MT3 (metallothionein 3); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GIF; growth inhibitory factor; metallothionein III; metallothionein-3; metallothionein-III; Mt-3; MT-III
Orthologs:
Homo sapiens (human) : MT3 (metallothionein 3)  HGNC  Alliance
Mus musculus (house mouse) : Mt3 (metallothionein 3)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MT3 (metallothionein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mt3 (metallothionein 3)
Sus scrofa (pig) : MT3 (metallothionein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01911,324,708 - 11,326,112 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01911,300,014 - 11,301,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41911,284,554 - 11,286,402 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11911,289,380 - 11,291,228 (-)NCBI
Celera1910,734,686 - 10,736,090 (-)NCBICelera
Cytogenetic Map19p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mt3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621252
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.