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Gene: Mmp2 (matrix metallopeptidase 2) Rattus norvegicus
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Symbol: Mmp2
Name: matrix metallopeptidase 2
Description: Exhibits fibronectin binding activity and peptidase activity. Involved in several processes, including cellular response to estradiol stimulus; circulatory system development; and reproductive structure development. Localizes to cytoplasm and extracellular space. Used to study artery disease (multiple); conjunctivitis; and ischemia (multiple). Biomarker of several diseases, including alcohol use disorder; artery disease (multiple); bile duct disease (multiple); brain ischemia (multiple); and liver cirrhosis (multiple). Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); ischemia; pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2); PARTICIPATES IN syndecan signaling pathway; gonadotropin-releasing hormone signaling pathway; urinary bladder cancer pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 72 kDa gelatinase; 72 KDa type IV collagenase; gelatinase A; matrix metalloproteinase 2; matrix metalloproteinase 2 (72 KDa type IV collagenase); matrix metalloproteinase-2; MMP-2
Orthologs:
Homo sapiens (human) : MMP2 (matrix metallopeptidase 2)  HGNC  Alliance
Mus musculus (house mouse) : Mmp2 (matrix metallopeptidase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp2 (matrix metallopeptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP2 (matrix metallopeptidase 2)
Canis lupus familiaris (dog) : MMP2 (matrix metallopeptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp2 (matrix metallopeptidase 2)
Sus scrofa (pig) : MMP2 (matrix metallopeptidase 2)
Chlorocebus sabaeus (African green monkey) : MMP2 (matrix metallopeptidase 2)
Heterocephalus glaber (naked mole-rat) : Mmp2 (matrix metallopeptidase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01915,542,771 - 15,570,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1915,542,765 - 15,570,611 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01926,629,728 - 26,658,966 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41915,246,036 - 15,275,061 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1914,077,766 - 14,105,839 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - curated
References - uncurated

Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 6.0)