Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ambra1 (autophagy and beclin 1 regulator 1) Rattus norvegicus
Analyze
Symbol: Ambra1
Name: autophagy and beclin 1 regulator 1
Description: Predicted to have GTPase binding activity and ubiquitin protein ligase binding activity. Involved in cellular response to starvation; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of autophagy. Predicted to colocalize with the mitochondrion. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1); PARTICIPATES IN inositol metabolic pathway; mitochondrial autophagy pathway; phosphoinositide metabolic pathway; INTERACTS WITH ammonium chloride; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: activating molecule in BECN1-regulated autophagy protein 1; autophagy/beclin 1 regulator 1; ischemia related factor NYW-1; Nyw1
Orthologs:
Homo sapiens (human) : AMBRA1 (autophagy and beclin 1 regulator 1)  HGNC  Alliance
Mus musculus (house mouse) : Ambra1 (autophagy/beclin 1 regulator 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ambra1 (autophagy and beclin 1 regulator 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AMBRA1 (autophagy and beclin 1 regulator 1)
Canis lupus familiaris (dog) : AMBRA1 (autophagy and beclin 1 regulator 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ambra1 (autophagy and beclin 1 regulator 1)
Sus scrofa (pig) : AMBRA1 (autophagy and beclin 1 regulator 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0380,634,470 - 80,830,068 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,634,470 - 80,830,068 (+)Ensembl
Rnor_5.0387,332,352 - 87,528,736 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4376,109,632 - 76,298,784 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1376,049,420 - 76,098,445 (+)NCBI
Celera376,904,996 - 77,092,869 (+)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ambra1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621330
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.