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Gene: Wnt2 (Wnt family member 2) Rattus norvegicus
Symbol: Wnt2
Name: Wnt family member 2
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in lung development and positive regulation of endothelial cell proliferation. Localizes to cytoplasm. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system cancer. Orthologous to human WNT2 (Wnt family member 2); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; basal cell carcinoma pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: protein Wnt-2; wingless-related MMTV integration site 2; wingless-type MMTV integration site 2; wingless-type MMTV integration site family member 2; Wnt
Homo sapiens (human) : WNT2 (Wnt family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Wnt2 (wingless-type MMTV integration site family, member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt2 (Wnt family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT2 (Wnt family member 2)
Canis lupus familiaris (dog) : WNT2 (Wnt family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt2 (Wnt family member 2)
Sus scrofa (pig) : WNT2 (Wnt family member 2)
Chlorocebus sabaeus (African green monkey) : WNT2 (Wnt family member 2)
Heterocephalus glaber (naked mole-rat) : Wnt2 (Wnt family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0445,286,845 - 45,332,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl445,292,437 - 45,332,420 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0445,892,395 - 45,936,605 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4443,649,783 - 43,689,596 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1443,857,074 - 43,859,488 (-)NCBI
Celera441,596,263 - 41,642,309 (-)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Wnt2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621346
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.