Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Myo5b (myosin Vb) Rattus norvegicus
Analyze
Symbol: Myo5b
Name: myosin Vb
Description: Exhibits several functions, including ATPase activity; Rab GTPase binding activity; and ionotropic glutamate receptor binding activity. Involved in several processes, including cellular response to glycine; generation of neurons; and positive regulation of exosomal secretion. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; cytoplasm; and postsynaptic actin cytoskeleton. Colocalizes with the recycling endosome. Human ortholog(s) of this gene implicated in microvillus inclusion disease. Orthologous to human MYO5B (myosin VB); PARTICIPATES IN vasopressin signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: myosin 5B; myosin heavy chain myr 6; Myosin of the dilute-myosin-V family; myosin-Vb; Myr6; unconventional myosin-Vb
Orthologs:
Homo sapiens (human) : MYO5B (myosin VB)  HGNC  Alliance
Mus musculus (house mouse) : Myo5b (myosin VB)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Myo5b (myosin VB)
Pan paniscus (bonobo/pygmy chimpanzee) : MYO5B (myosin VB)
Canis lupus familiaris (dog) : MYO5B (myosin VB)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Myo5b (myosin VB)
Sus scrofa (pig) : MYO5B (myosin VB)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01870,426,865 - 70,729,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01869,568,169 - 69,869,070 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41871,381,068 - 71,580,824 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11871,454,267 - 71,654,025 (+)NCBI
Celera1866,217,242 - 66,515,213 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Myo5b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621347
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.