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Gene: Kcne2 (potassium voltage-gated channel subfamily E regulatory subunit 2) Rattus norvegicus
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Symbol: Kcne2
Name: potassium voltage-gated channel subfamily E regulatory subunit 2
Description: Exhibits several functions, including ion channel binding activity; potassium channel regulator activity; and protein homodimerization activity. Contributes to delayed rectifier potassium channel activity and inward rectifier potassium channel activity. Involved in several processes, including aging; potassium ion transmembrane transport; and regulation of ion transmembrane transport. Localizes to the cell surface; cytoplasm; and voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in atrial fibrillation; familial atrial fibrillation; long QT syndrome; and long QT syndrome 6. Orthologous to human KCNE2 (potassium voltage-gated channel subfamily E regulatory subunit 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC108602; minimum potassium ion channel-related peptide 1; minK-related peptide 1; Mirp1; potassium channel subunit beta MiRP1; potassium channel, voltage gated subfamily E regulatory beta subunit 2; potassium channel, voltage-gated Isk-related subfamily E regulatory beta subunit 2; potassium voltage-gated channel subfamily E member 2; potassium voltage-gated channel, Isk-related family, member 2; potassium voltage-gated channel, Isk-related subfamily, gene 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01132,434,786 - 32,447,264 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01136,038,539 - 36,051,121 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41132,277,711 - 32,290,828 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11132,339,411 - 32,347,070 (+)NCBI
Celera1131,171,793 - 31,183,884 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kcne2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621383
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.