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Gene: Slco1a4 (solute carrier organic anion transporter family, member 1a4) Rattus norvegicus
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Symbol: Slco1a4
Name: solute carrier organic anion transporter family, member 1a4
Description: Exhibits bile acid transmembrane transporter activity. Involved in sodium-independent organic anion transport. Localizes to the basal plasma membrane and cell surface. Biomarker of Dubin-Johnson syndrome and fatty liver disease. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2); PARTICIPATES IN multispecific organic anion transporter mediated transport pathway; bile acid transport pathway; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: brain digoxin carrier protein; brain-specific organic anion transporter; OATP-B1; Oatp2; organic anion transporter 2; Slc21a5; Slco1a2; sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 5; solute carrier family 21 member 5; solute carrier organic anion transporter family member 1A4; solute carrier organic anion transporter family, member 1A2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04175,969,549 - 176,026,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4175,969,549 - 176,026,163 (-)Ensembl
Rnor_5.04240,194,947 - 240,251,561 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4163,247,039 - 163,301,862 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slco1a4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621389
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.