Gene: Ghsr (growth hormone secretagogue receptor) Rattus norvegicus
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Symbol: Ghsr
Name: growth hormone secretagogue receptor
Description: Exhibits growth hormone secretagogue receptor activity and peptide hormone binding activity; involved in several processes, including cellular response to hormone stimulus, regulation of digestive system process, and regulation of secretion; localizes to the Schaffer collateral - CA1 synapse, glutamatergic synapse, and integral component of synaptic membrane; used to study middle cerebral artery infarction; biomarker of isolated growth hormone deficiency, obstructive sleep apnea, status epilepticus, and transient cerebral ischemia; orthologous to human GHSR (growth hormone secretagogue receptor); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; ghrelin system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GH-releasing peptide receptor; ghrelin receptor; GHRP; GHS-R; growth hormone secretagogue receptor type 1
Orthologs:
Homo sapiens (human) : GHSR (growth hormone secretagogue receptor)  HGNC  Alliance
Mus musculus (house mouse) : Ghsr (growth hormone secretagogue receptor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ghsr (growth hormone secretagogue receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : GHSR (growth hormone secretagogue receptor)
Canis lupus familiaris (dog) : GHSR (growth hormone secretagogue receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ghsr (growth hormone secretagogue receptor)
Sus scrofa (pig) : GHSR (growth hormone secretagogue receptor)
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Allele / Splice: Ghsrm1Mcwi   Ghsrm2Mcwi   Ghsrm3Mcwi   Ghsrem1Ottc  
Genetic Models: FHH-Ghsrm1Mcwi SS-Ghsrm2Mcwi SS-Ghsrm3Mcwi W-Ghsrem1Ottc
Is Marker For: Strains:   SD-Tg(Th-Ghsros)  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02113,065,953 - 113,071,265 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02132,784,207 - 132,789,319 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42113,269,623 - 113,272,999 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12113,214,584 - 113,217,961 (+)NCBI
Celera2105,470,925 - 105,474,301 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ghsr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621397
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.