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Gene: Skil (SKI-like proto-oncogene) Rattus norvegicus
Symbol: Skil
Name: SKI-like proto-oncogene
CRRD ID: 621399
Description: Predicted to have several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; SMAD binding activity; and identical protein binding activity. Involved in positive regulation of axonogenesis; response to cytokine; and spermatogenesis. Localizes to acrosomal vesicle and nucleus. Biomarker of ureteral obstruction. Orthologous to human SKIL (SKI like proto-oncogene); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: SKI-like; SKI-like oncogene; ski/sno related; Skir; Sno
Homo sapiens (human) : SKIL (SKI like proto-oncogene)  HGNC  Alliance
Mus musculus (house mouse) : Skil (SKI-like)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Skil (SKI like proto-oncogene)
Pan paniscus (bonobo/pygmy chimpanzee) : SKIL (SKI like proto-oncogene)
Canis lupus familiaris (dog) : SKIL (SKI like proto-oncogene)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Skil (SKI like proto-oncogene)
Sus scrofa (pig) : SKIL (SKI like proto-oncogene)
Chlorocebus sabaeus (African green monkey) : SKIL (SKI like proto-oncogene)
Heterocephalus glaber (naked mole-rat) : Skil (SKI like proto-oncogene)
more info ...
Allele / Splice: Skil_v1   Skil_v2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02115,862,932 - 115,891,304 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2115,866,701 - 115,891,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02135,558,909 - 135,587,255 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,669,375 - 116,691,472 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12116,636,239 - 116,636,434 (-)NCBI
Celera2107,434,508 - 107,462,883 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Skil
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621399
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.