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Gene: Kpna2 (karyopherin subunit alpha 2) Rattus norvegicus
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Symbol: Kpna2
Name: karyopherin subunit alpha 2
Description: Predicted to have histone deacetylase binding activity; nuclear localization sequence binding activity; and repressing transcription factor binding activity. Involved in regulation of transcription by glucose. Predicted to localize to several cellular components, including the cytoplasm; extrinsic component of postsynaptic specialization membrane; and nucleoplasm. Orthologous to human KPNA2 (karyopherin subunit alpha 2); PARTICIPATES IN influenza A pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: importin; importin subunit alpha-1; importin subunit alpha-2; karyopherin (importin) alpha 2; karyopherin alpha 2; MGC108637; nuclear import protein
Orthologs:
Homo sapiens (human) : KPNA2 (karyopherin subunit alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : Kpna2 (karyopherin (importin) alpha 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kpna2 (karyopherin subunit alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : KPNA2 (karyopherin subunit alpha 2)
Canis lupus familiaris (dog) : KPNA2 (karyopherin subunit alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kpna2 (karyopherin subunit alpha 2)
Sus scrofa (pig) : KPNA2 (karyopherin subunit alpha 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01095,200,029 - 95,212,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,940,856 - 94,952,938 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41096,342,214 - 96,352,613 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11096,356,583 - 96,366,983 (-)NCBI
Celera1090,599,417 - 90,611,576 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kpna2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621419
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.