Gene: Klf4 (Kruppel like factor 4) Rattus norvegicus
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Symbol: Klf4
Name: Kruppel like factor 4
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific, histone deacetylase binding activity, and nucleic acid binding activity; involved in several processes, including cellular response to organonitrogen compound, negative regulation of intracellular signal transduction, and regulation of cellular biosynthetic process; localizes to the chromatin, nucleus, and transcription factor complex; orthologous to human KLF4 (Kruppel like factor 4); INTERACTS WITH (-)-epigallocatechin 3-gallate; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GKLF; Krueppel-like factor 4; Kruppel-like factor 4 (gut); MGC93286
Orthologs:
Homo sapiens (human) : KLF4 (Kruppel like factor 4)  HGNC  Alliance
Mus musculus (house mouse) : Klf4 (Kruppel-like factor 4 (gut))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf4 (Kruppel like factor 4)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF4 (Kruppel like factor 4)
Canis lupus familiaris (dog) : KLF4 (Kruppel like factor 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf4 (Kruppel like factor 4)
Sus scrofa (pig) : KLF4 (Kruppel like factor 4)
more info ...
Allele / Splice: Klf4m2Mcwi   Klf4m1Mcwi   Klf4m3Mcwi  
Genetic Models: SS-Klf4m2Mcwi SS-Klf4m1Mcwi SS-Klf4m3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0572,283,311 - 72,287,669 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0576,447,643 - 76,452,001 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4573,446,928 - 73,451,286 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1573,452,042 - 73,456,399 (-)NCBI
Celera569,133,658 - 69,138,016 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Klf4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621445
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.