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Gene: Klf5 (Kruppel-like factor 5) Rattus norvegicus
Symbol: Klf5
Name: Kruppel-like factor 5
Description: Exhibits sequence-specific DNA binding activity and transcription factor binding activity. Involved in several processes, including cellular response to peptide; negative regulation of cardiac vascular smooth muscle cell differentiation; and positive regulation of cell population proliferation. Predicted to localize to the Golgi apparatus; nucleoplasm; and transcription factor complex. Orthologous to human KLF5 (Kruppel like factor 5); INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: basic transcription element binding protein 2; basic transcription element binding protein BTEB2; Bteb2; IKLF; Krueppel-like factor 5; Kruppel-like factor 5 (intestinal)
Homo sapiens (human) : KLF5 (Kruppel like factor 5)  HGNC  Alliance
Mus musculus (house mouse) : Klf5 (Kruppel-like factor 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf5 (Kruppel like factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF5 (Kruppel like factor 5)
Canis lupus familiaris (dog) : KLF5 (Kruppel like factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf5 (Kruppel like factor 5)
Sus scrofa (pig) : KLF5 (Kruppel like factor 5)
more info ...
Related Pseudogenes: Klf5-ps1   Klf5-ps2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01583,703,796 - 83,722,921 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01587,212,719 - 87,231,850 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41583,103,177 - 83,118,363 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11583,121,895 - 83,132,620 (+)NCBI
Celera1575,305,416 - 75,320,302 (+)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Klf5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621446
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.