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Gene: Kcnk1 (potassium two pore domain channel subfamily K member 1) Rattus norvegicus
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Symbol: Kcnk1
Name: potassium two pore domain channel subfamily K member 1
Description: Exhibits potassium ion leak channel activity. Involved in potassium ion transmembrane transport and response to nicotine. Localizes to several cellular components, including apical plasma membrane; brush border membrane; and integral component of plasma membrane. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inward rectifying potassium channel protein TWIK-1; potassium channel K2P1; potassium channel subfamily K member 1; potassium channel, subfamily K, member 1; potassium channel, two pore domain subfamily K, member 1; putative potassium channel TWIK; rTWIK; Twik
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01958,823,836 - 58,862,926 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1958,823,814 - 58,862,926 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01969,519,015 - 69,556,610 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41956,216,600 - 56,255,299 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11956,221,480 - 56,260,178 (+)NCBI
Celera1953,319,777 - 53,357,303 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kcnk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621447
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.