Gene: Twist1 (twist family bHLH transcription factor 1) Rattus norvegicus
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Symbol: Twist1
Name: twist family bHLH transcription factor 1
Description: Predicted to have several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding activity, and protein dimerization activity; involved in several processes, including animal organ development, cellular response to growth factor stimulus, and negative regulation of apoptotic process; localizes to the nucleus; orthologous to human TWIST1 (twist family bHLH transcription factor 1); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Twist; twist basic helix-loop-helix transcription factor 1; twist gene homolog 1; twist gene homolog 1 (Drosophila); twist gene homolog, (Drosophila); twist homolog 1; twist homolog 1 (Drosophila); twist-related protein 1
Orthologs:
Homo sapiens (human) : TWIST1 (twist family bHLH transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Twist1 (twist basic helix-loop-helix transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Twist1 (twist family bHLH transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TWIST1 (twist family bHLH transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Twist1 (twist family bHLH transcription factor 1)
Sus scrofa (pig) : TWIST1 (twist family bHLH transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0653,401,241 - 53,403,235 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0663,023,523 - 63,025,517 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4652,605,869 - 52,607,863 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1652,609,172 - 52,609,784 (+)NCBI
Celera649,841,416 - 49,843,227 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Twist1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621455
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.