Gene: Kcnq1 (potassium voltage-gated channel subfamily Q member 1) Rattus norvegicus
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Symbol: Kcnq1
Name: potassium voltage-gated channel subfamily Q member 1
Description: Exhibits delayed rectifier potassium channel activity, outward rectifier potassium channel activity, and protein homodimerization activity; involved in several processes, including intestinal absorption, male gonad development, and regulation of secretion; localizes to several cellular components, including the basolateral plasma membrane, sarcolemma, and voltage-gated potassium channel complex; predicted to colocalize with the early endosome; used to study hypertension; orthologous to human KCNQ1 (potassium voltage-gated channel subfamily Q member 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; ammonium chloride; bis(2-chloroethyl) sulfide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; KQT-like 1; Kvlqt1; potassium channel, voltage-gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; potassium voltage-gated channel, subfamily Q, member 1; voltage-gated potassium channel subunit Kv7.1
Orthologs:
Allele / Splice: Kcnq1em9Mcwi   Kcnq1em14Mcwi   Kcnq1dfk   Kcnq1em5Mcwi  
Genetic Models: WTC-Kcnq1dfkKyo SS-Kcnq1em5Mcwi SS-Kcnq1em14Mcwi SS-Kcnq1em9Mcwi
Is Marker For: Strains:   WTC-Kcnq1dfkKyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01216,293,087 - 216,630,339 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01223,154,713 - 223,490,458 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41203,383,401 - 203,803,687 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11203,536,853 - 203,957,140 (+)NCBI
Celera1195,860,199 - 196,193,008 (+)NCBICelera
Cytogenetic Map1q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)