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Gene: Slc22a12 (solute carrier family 22 member 12) Rattus norvegicus
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Symbol: Slc22a12
Name: solute carrier family 22 member 12
Description: Predicted to have PDZ domain binding activity and urate transmembrane transporter activity. Involved in cellular response to insulin stimulus and urate salt excretion. Localizes to the apical plasma membrane. Biomarker of diabetes mellitus. Orthologous to human SLC22A12 (solute carrier family 22 member 12); INTERACTS WITH 2-hydroxypropanoic acid; 6-propyl-2-thiouracil; 7,9-dihydro-1H-purine-2,6,8(3H)-trione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC365398; MGC124974; Rst; Slc22al2; solute carrier family 22 (organic anion/cation transporter), member 12; solute carrier family 22 (organic anion/urate transporter), member 12; solute carrier family 22 (organic cation transporter)-like 2; URAT1; urate anion exchanger 1
Orthologs:
Homo sapiens (human) : SLC22A12 (solute carrier family 22 member 12)  HGNC  Alliance
Mus musculus (house mouse) : Slc22a12 (solute carrier family 22 (organic anion/cation transporter), member 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc22a12 (solute carrier family 22 member 12)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A12 (solute carrier family 22 member 12)
Canis lupus familiaris (dog) : SLC22A12 (solute carrier family 22 member 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a12 (solute carrier family 22 member 12)
Sus scrofa (pig) : SLC22A12 (solute carrier family 22 member 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01221,910,787 - 221,919,277 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01228,902,080 - 228,910,569 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,320,804 - 209,327,918 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,479,477 - 209,480,301 (-)NCBI
Celera1201,379,795 - 201,386,875 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Slc22a12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621628
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.