Gene: Itga6 (integrin subunit alpha 6) Rattus norvegicus
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Symbol: Itga6
Name: integrin subunit alpha 6
Description: Exhibits laminin binding activity; involved in cell-cell adhesion, cellular response to organic cyclic compound, and positive regulation of cell-substrate adhesion; localizes to the cell-cell adherens junction, filopodium, and integrin alpha6-beta4 complex; orthologous to human ITGA6 (integrin subunit alpha 6); PARTICIPATES IN integrin mediated signaling pathway; arrhythmogenic right ventricular cardiomyopathy pathway; cell-extracellular matrix signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: integrin alpha-6; integrin, alpha 6
Orthologs:
Homo sapiens (human) : ITGA6 (integrin subunit alpha 6)  HGNC  Alliance
Mus musculus (house mouse) : Itga6 (integrin alpha 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga6 (integrin subunit alpha 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA6 (integrin subunit alpha 6)
Canis lupus familiaris (dog) : ITGA6 (integrin subunit alpha 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga6 (integrin subunit alpha 6)
Sus scrofa (pig) : ITGA6 (integrin subunit alpha 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0358,442,904 - 58,515,124 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0364,931,497 - 65,003,370 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4354,202,931 - 54,272,803 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1354,134,160 - 54,168,913 (+)NCBI
Celera356,160,628 - 56,232,455 (+)NCBICelera
Cytogenetic Map3q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Itga6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621633
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.