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Gene: Fads1 (fatty acid desaturase 1) Rattus norvegicus
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Symbol: Fads1
Name: fatty acid desaturase 1
Description: Exhibits oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. Involved in several processes, including aging; response to vitamin A; and unsaturated fatty acid metabolic process. Localizes to the nucleus. Biomarker of hypertension and obesity. Orthologous to human FADS1 (fatty acid desaturase 1); PARTICIPATES IN alpha-linoleic acid metabolic pathway; linoleic acid metabolic pathway; unsaturated fatty acid biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; (+)-sesamin; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: acyl-CoA (8-3)-desaturase; D5D; delta(5) desaturase; delta(5) fatty acid desaturase; delta-5 desaturase
Orthologs:
Homo sapiens (human) : FADS1 (fatty acid desaturase 1)  HGNC  Alliance
Mus musculus (house mouse) : Fads1 (fatty acid desaturase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fads1 (fatty acid desaturase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FADS1 (fatty acid desaturase 1)
Canis lupus familiaris (dog) : FADS1 (fatty acid desaturase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fads1 (fatty acid desaturase 1)
Sus scrofa (pig) : FADS1 (fatty acid desaturase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01226,234,034 - 226,249,118 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01233,178,735 - 233,193,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,670,792 - 212,685,718 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,829,200 - 212,844,142 (+)NCBI
Celera1204,324,218 - 204,339,144 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fads1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621678
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.