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Gene: Atox1 (antioxidant 1 copper chaperone) Rattus norvegicus
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Symbol: Atox1
Name: antioxidant 1 copper chaperone
Description: Exhibits ATPase binding activity. Involved in copper ion export; negative regulation of apoptotic process; and response to oxidative stress. Predicted to localize to the cytosol. Orthologous to human ATOX1 (antioxidant 1 copper chaperone); PARTICIPATES IN cisplatin drug pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Atx1; ATX1 (antioxidant protein 1) homolog 1; ATX1 (antioxidant protein 1) homolog 1 (yeast); ATX1 antioxidant protein 1 homolog; ATX1 antioxidant protein 1 homolog (yeast); ATX1 homolog protein Rah1; copper transport protein ATOX1; metal transport protein ATX1
Orthologs:
Homo sapiens (human) : ATOX1 (antioxidant 1 copper chaperone)  HGNC  Alliance
Mus musculus (house mouse) : Atox1 (antioxidant 1 copper chaperone)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atox1 (antioxidant 1 copper chaperone)
Pan paniscus (bonobo/pygmy chimpanzee) : ATOX1 (antioxidant 1 copper chaperone)
Canis lupus familiaris (dog) : ATOX1 (antioxidant 1 copper chaperone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atox1 (antioxidant 1 copper chaperone)
Sus scrofa (pig) : ATOX1 (antioxidant 1 copper chaperone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01040,790,850 - 40,805,886 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01040,622,323 - 40,637,362 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41040,858,190 - 40,873,226 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11040,871,817 - 40,886,834 (-)NCBI
Celera1038,896,595 - 38,911,631 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atox1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621684
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.