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Gene: Sftpb (surfactant protein B) Rattus norvegicus
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Symbol: Sftpb
Name: surfactant protein B
Description: Involved in several processes, including cellular response to mechanical stimulus; cellular response to nitric oxide; and response to vitamin A. Localizes to the alveolar lamellar body; extracellular space; and multivesicular body. Biomarker of asthma; bacterial pneumonia; lung disease; newborn respiratory distress syndrome; and obesity. Human ortholog(s) of this gene implicated in lung disease (multiple); respiratory syncytial virus infectious disease; and toxic shock syndrome. Orthologous to human SFTPB (surfactant protein B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; all-trans-retinol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: pulmonary surfactant-associated protein B; pulmonary surfactant-associated proteolipid SPL(Phe); Sp-b; surfactant associated protein B; surfactant pulmonary-associated protein B; surfactant, pulmonary-associated protein B
Orthologs:
Homo sapiens (human) : SFTPB (surfactant protein B)  HGNC  Alliance
Mus musculus (house mouse) : Sftpb (surfactant associated protein B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sftpb (surfactant protein B)
Pan paniscus (bonobo/pygmy chimpanzee) : SFTPB (surfactant protein B)
Canis lupus familiaris (dog) : SFTPB (surfactant protein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sftpb (surfactant protein B)
Sus scrofa (pig) : SFTPB (surfactant protein B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04100,166,855 - 100,175,941 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04164,937,638 - 164,946,703 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44105,609,410 - 105,618,452 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14105,853,890 - 105,862,933 (+)NCBI
Celera493,513,449 - 93,522,486 (+)NCBICelera
Cytogenetic Map4q31NCBI
RH 3.4 Map4631.95RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sftpb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621700
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.