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Gene: Gpt (glutamic--pyruvic transaminase) Rattus norvegicus
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Symbol: Gpt
Name: glutamic--pyruvic transaminase
Description: Predicted to have L-alanine:2-oxoglutarate aminotransferase activity. Involved in cellular response to insulin stimulus; positive regulation of gluconeogenesis; and response to starvation. Localizes to the cytoplasm and extracellular space. Biomarker of type 2 diabetes mellitus. Orthologous to human GPT (glutamic--pyruvic transaminase); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; alanine metabolic pathway; argininosuccinic aciduria pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (E)-thiamethoxam.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alanine aminotransferase 1; ALAT; ALT1; glutamate pyruvate transaminase 1; glutamic pyruvate transaminase; glutamic pyruvic transaminase (alanine aminotrasferase); glutamic pyruvic transaminase 1, soluble; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamic-pyruvate transaminase (alanine aminotransferase); GPT 1; Gpt1
Orthologs:
Homo sapiens (human) : GPT (glutamic--pyruvic transaminase)  HGNC  Alliance
Mus musculus (house mouse) : Gpt (glutamic pyruvic transaminase, soluble)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpt (glutamic--pyruvic transaminase)
Pan paniscus (bonobo/pygmy chimpanzee) : GPT (glutamic--pyruvic transaminase)
Canis lupus familiaris (dog) : GPT (glutamic--pyruvic transaminase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpt (glutamic--pyruvic transaminase)
Sus scrofa (pig) : GPT (glutamic--pyruvic transaminase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07117,759,083 - 117,761,932 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,759,083 - 117,761,931 (+)Ensembl
Rnor_5.07117,745,308 - 117,749,938 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,746,054 - 114,748,903 (+)NCBIRGSC3.4rn4RGSC3.4
Celera7104,766,538 - 104,769,387 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gpt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621720
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.