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Gene: Foxe3 (forkhead box E3) Rattus norvegicus
Symbol: Foxe3
Name: forkhead box E3
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in several processes, including camera-type eye development; mRNA transcription by RNA polymerase II; and negative regulation of cell cycle arrest. Predicted to localize to nucleus and transcription regulator complex. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; anterior segment dysgenesis 2; cataract 34 multiple types; and thoracic aortic aneurysm. Orthologous to human FOXE3 (forkhead box E3); INTERACTS WITH ammonium chloride; bisphenol A; capsaicin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: forkhead box protein E3; forkhead-related protein FKHL12; forkhead-related transcription factor 8; FREAC-8; hepatocyte nuclear factor 3 forkhead homolog 7; HFH-7; HFH7; HNF3; LOC313505
Homo sapiens (human) : FOXE3 (forkhead box E3)  HGNC  Alliance
Mus musculus (house mouse) : Foxe3 (forkhead box E3)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FOXE3 (forkhead box E3)
Canis lupus familiaris (dog) : FOXE3 (forkhead box E3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxe3 (forkhead box E3)
Sus scrofa (pig) : FOXE3 (forkhead box E3)
Chlorocebus sabaeus (African green monkey) : FOXE3 (forkhead box E3)
Heterocephalus glaber (naked mole-rat) : Foxe3 (forkhead box E3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05133,724,796 - 133,725,656 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5133,724,796 - 133,725,656 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05137,517,035 - 137,517,895 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,285,688 - 135,286,548 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15135,291,289 - 135,291,591 (-)NCBI
Celera5127,097,587 - 127,098,447 (-)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Foxe3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621727
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.