Gene: Flt4 (fms-related tyrosine kinase 4) Rattus norvegicus
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Symbol: Flt4
Name: fms-related tyrosine kinase 4
Description: Exhibits growth factor binding activity and vascular endothelial growth factor-activated receptor activity; involved in positive regulation of cell growth and vascular endothelial growth factor receptor signaling pathway; predicted to localize to the integral component of plasma membrane, nucleoplasm, and receptor complex; orthologous to human FLT4 (fms related tyrosine kinase 4); PARTICIPATES IN vascular endothelial growth factor signaling pathway; altered vascular endothelial growth factor signaling pathway; altered vascular endothelial growth factor signaling pathway involving the main players; INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FLT-4; FMS-like tyrosine kinase 4; LOC360235; tyrosine-protein kinase receptor FLT4; vascular endothelial growth factor receptor 3; VEGFR-3; Vegfr3
Orthologs:
Homo sapiens (human) : FLT4 (fms related tyrosine kinase 4)  HGNC  Alliance
Mus musculus (house mouse) : Flt4 (FMS-like tyrosine kinase 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flt4 (fms related tyrosine kinase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FLT4 (fms related tyrosine kinase 4)
Canis lupus familiaris (dog) : FLT4 (fms related tyrosine kinase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flt4 (fms related tyrosine kinase 4)
Sus scrofa (pig) : FLT4 (fms related tyrosine kinase 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01035,078,782 - 35,120,296 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01034,850,707 - 34,892,141 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,071,002 - 35,112,006 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11035,072,050 - 35,113,055NCBI
Celera1033,270,535 - 33,311,432 (+)NCBICelera
Cytogenetic Map10q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Flt4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621737
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.