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Gene: Casp4 (caspase 4) Rattus norvegicus
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Symbol: Casp4
Name: caspase 4
Description: Exhibits scaffold protein binding activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; ectopic germ cell programmed cell death; and positive regulation of interleukin-1 beta secretion. Localizes to the neuron projection; neuronal cell body; and protein-containing complex. Orthologous to several human genes including CASP4 (caspase 4); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Casp11; caspase 11; caspase 4, apoptosis-related cysteine peptidase; MGC124949
Orthologs:
Homo sapiens (human) : CASP4 (caspase 4)  HGNC  Alliance
Mus musculus (house mouse) : Casp4 (caspase 4, apoptosis-related cysteine peptidase)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CASP4 (caspase 4)
Canis lupus familiaris (dog) : CASP4 (caspase 4, apoptosis-related cysteine peptidase)
Sus scrofa (pig) : LOC100522887 (caspase-13)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.082,616,391 - 2,651,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.082,638,624 - 2,673,915 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.482,038,626 - 2,075,722 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.182,038,610 - 2,075,144 (+)NCBI
Celera84,218,310 - 4,234,223 (+)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Casp4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621757
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.