Gene: Slpi (secretory leukocyte peptidase inhibitor) Rattus norvegicus
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Symbol: Slpi
Name: secretory leukocyte peptidase inhibitor
Description: Predicted to have enzyme binding activity, nucleic acid binding activity, and serine-type endopeptidase inhibitor activity; involved in negative regulation of inflammatory response; predicted to localize to the extracellular space; biomarker of chronic obstructive pulmonary disease, endophthalmitis, middle cerebral artery infarction, myocardial infarction, and polycystic ovary syndrome; orthologous to human SLPI (secretory leukocyte peptidase inhibitor); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: secretory leukocyte protease inhibitor
Orthologs:
Homo sapiens (human) : SLPI (secretory leukocyte peptidase inhibitor)  HGNC  Alliance
Mus musculus (house mouse) : Slpi (secretory leukocyte peptidase inhibitor)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : SLPI (secretory leukocyte peptidase inhibitor)
Canis lupus familiaris (dog) : SLPI (secretory leukocyte peptidase inhibitor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slpi (secretory leukocyte peptidase inhibitor)
Sus scrofa (pig) : SLPI (secretory leukocyte peptidase inhibitor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03160,799,979 - 160,802,228 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03166,981,037 - 166,983,286 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,373,825 - 155,376,074 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13155,279,861 - 155,282,110 (-)NCBI
Celera3151,693,623 - 151,695,872 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slpi
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621768
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.