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Gene: Dhcr7 (7-dehydrocholesterol reductase) Rattus norvegicus
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Symbol: Dhcr7
Name: 7-dehydrocholesterol reductase
Description: Exhibits 7-dehydrocholesterol reductase activity. Involved in cholesterol biosynthetic process and regulation of cholesterol biosynthetic process. Localizes to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Smith-Lemli-Opitz syndrome. Orthologous to human DHCR7 (7-dehydrocholesterol reductase); PARTICIPATES IN cholesterol biosynthetic pathway; steroid biosynthetic pathway; INTERACTS WITH (RS)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 7-DHC reductase; MGC93039; sterol Delta(7)-reductase
Orthologs:
Homo sapiens (human) : DHCR7 (7-dehydrocholesterol reductase)  HGNC  Alliance
Mus musculus (house mouse) : Dhcr7 (7-dehydrocholesterol reductase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhcr7 (7-dehydrocholesterol reductase)
Pan paniscus (bonobo/pygmy chimpanzee) : DHCR7 (7-dehydrocholesterol reductase)
Canis lupus familiaris (dog) : DHCR7 (7-dehydrocholesterol reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhcr7 (7-dehydrocholesterol reductase)
Sus scrofa (pig) : DHCR7 (7-dehydrocholesterol reductase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01217,018,916 - 217,034,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01223,874,935 - 223,890,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41204,245,562 - 204,258,913 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11204,399,014 - 204,412,366 (+)NCBI
Celera1196,577,886 - 196,593,821 (+)NCBICelera
Cytogenetic Map1q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dhcr7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621769
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.