Gene: Dkc1 (dyskerin pseudouridine synthase 1) Rattus norvegicus
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Symbol: Dkc1
Name: dyskerin pseudouridine synthase 1
Description: Predicted to have RNA binding activity, pseudouridine synthase activity, and telomerase activity; involved in positive regulation of cell population proliferation and snoRNA guided rRNA pseudouridine synthesis; localizes to the Cajal body and box H/ACA snoRNP complex; orthologous to human DKC1 (dyskerin pseudouridine synthase 1); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dyskeratosis congenita 1, dyskerin; dyskerin; h/ACA ribonucleoprotein complex subunit 4; H/ACA ribonucleoprotein complex subunit DKC1; Nap57; nopp140-associated protein of 57 kDa; nucleolar protein family A member 4; nucleolar protein NAP57; snoRNP protein DKC1
Orthologs:
Homo sapiens (human) : DKC1 (dyskerin pseudouridine synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Dkc1 (dyskeratosis congenita 1, dyskerin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dkc1 (dyskerin pseudouridine synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DKC1 (dyskerin pseudouridine synthase 1)
Canis lupus familiaris (dog) : DKC1 (dyskerin pseudouridine synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkc1 (dyskerin pseudouridine synthase 1)
Sus scrofa (pig) : DKC1 (dyskerin pseudouridine synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X155,844,914 - 155,862,363 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01151,564,354 - 151,578,635 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1135,295,501 - 135,310,658 (-)ENTREZGENECelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dkc1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621780
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.