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Gene: Dnah1 (dynein, axonemal, heavy chain 1) Rattus norvegicus
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Symbol: Dnah1
Name: dynein, axonemal, heavy chain 1
Description: Predicted to have several functions, including ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light chain binding activity. Predicted to be involved in axoneme assembly; cilium movement involved in cell motility; and epithelial cilium movement involved in extracellular fluid movement. Predicted to localize to the inner dynein arm and sperm flagellum. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Orthologous to human DNAH1 (dynein axonemal heavy chain 1); PARTICIPATES IN Huntington's disease pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: axonemal beta dynein heavy chain 1; ciliary dynein heavy chain 1; Dnahc1; dynein heavy chain 1, axonemal; dynein, axonemal, heavy polypeptide 1; LOC306258; RGD1311110; similar to KIAA1410 protein
Orthologs:
Homo sapiens (human) : DNAH1 (dynein axonemal heavy chain 1)  HGNC  Alliance
Mus musculus (house mouse) : Dnah1 (dynein, axonemal, heavy chain 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dnah1 (dynein axonemal heavy chain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DNAH1 (dynein axonemal heavy chain 1)
Canis lupus familiaris (dog) : DNAH1 (dynein axonemal heavy chain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dnah1 (dynein axonemal heavy chain 1)
Sus scrofa (pig) : DNAH1 (dynein axonemal heavy chain 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0167,345,131 - 7,407,009 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0167,273,266 - 7,336,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,693,763 - 6,754,535 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1166,724,485 - 6,726,552 (-)NCBI
Celera168,672,026 - 8,733,031 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Dnah1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621795
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.