Gene: Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3) Rattus norvegicus
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Symbol: Hsd17b3
Name: hydroxysteroid (17-beta) dehydrogenase 3
Description: Exhibits estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity; involved in several processes, including animal organ development, biphenyl metabolic process, and response to vitamin; localizes to the intracellular membrane-bounded organelle; biomarker of type 2 diabetes mellitus; orthologous to human HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 17-beta-HSD 3; 17-beta-hydroxysteroid dehydrogenase type 3; 17beta-HSD; estradiol 17 beta-dehydrogenase 3; hydroxysteroid 17-beta dehydrogenase 3; testicular 17-beta-hydroxysteroid dehydrogenase; testosterone 17-beta-dehydrogenase 3
Orthologs:
Homo sapiens (human) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)  HGNC  Alliance
Mus musculus (house mouse) : Hsd17b3 (hydroxysteroid (17-beta) dehydrogenase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Canis lupus familiaris (dog) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hsd17b3 (hydroxysteroid 17-beta dehydrogenase 3)
Sus scrofa (pig) : HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0171,579,319 - 1,610,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0171,570,077 - 1,600,357 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,554,164 - 6,585,525 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1176,554,163 - 6,585,525 (+)NCBI
Celera171,458,596 - 1,490,020 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hsd17b3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621805
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.