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Gene: Cngb1 (cyclic nucleotide gated channel subunit beta 1) Rattus norvegicus
Symbol: Cngb1
Name: cyclic nucleotide gated channel subunit beta 1
Description: Exhibits intracellular cAMP-activated cation channel activity and intracellular cGMP-activated cation channel activity. Involved in protein heterotetramerization and regulation of cytosolic calcium ion concentration. Localizes to the intracellular cyclic nucleotide activated cation channel complex; plasma membrane; and terminal bouton. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 45. Orthologous to human CNGB1 (cyclic nucleotide gated channel beta 1); PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; INTERACTS WITH 1-naphthyl isothiocyanate; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: cyclic nucleotide gated channel beta 1; cyclic nucleotide-gated cation channel beta-1; cyclic nucleotide-gated channel beta subunit 1; gene model 1959, (NCBI); Gm1959; LOC360297
Homo sapiens (human) : CNGB1 (cyclic nucleotide gated channel subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Cngb1 (cyclic nucleotide gated channel beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cngb1 (cyclic nucleotide gated channel subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNGB1 (cyclic nucleotide gated channel subunit beta 1)
Canis lupus familiaris (dog) : CNGB1 (cyclic nucleotide gated channel subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cngb1 (cyclic nucleotide gated channel subunit beta 1)
Sus scrofa (pig) : CNGB1 (cyclic nucleotide gated channel subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01910,142,440 - 10,206,618 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01910,126,285 - 10,190,852 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,186,416 - 10,257,296 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11910,191,241 - 10,262,122NCBI
Celera199,619,420 - 9,683,573 (+)NCBICelera
Cytogenetic Map19p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cngb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621809
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.