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Gene: Cnga1 (cyclic nucleotide gated channel subunit alpha 1) Rattus norvegicus
Symbol: Cnga1
Name: cyclic nucleotide gated channel subunit alpha 1
CRRD ID: 621815
Description: Exhibits cGMP binding activity and intracellular cGMP-activated cation channel activity. Involved in membrane depolarization; regulation of cytosolic calcium ion concentration; and spermatogenesis. Localizes to cytoplasm; intracellular cyclic nucleotide activated cation channel complex; and terminal bouton. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1); PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: cGMP-gated cation channel alpha-1; Cncg; CNG channel alpha-1; CNG-1; CNG1; cyclic nucleotide gated channel alpha 1; cyclic nucleotide-gated cation channel; cyclic nucleotide-gated cation channel 1; cyclic nucleotide-gated channel alpha-1; cyclic nucleotide-gated channel, photoreceptor; HCN; rod photoreceptor cGMP-gated channel subunit alpha
Homo sapiens (human) : CNGA1 (cyclic nucleotide gated channel subunit alpha 1)  HGNC  Alliance
Mus musculus (house mouse) : Cnga1 (cyclic nucleotide gated channel alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnga1 (cyclic nucleotide gated channel subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNGA1 (cyclic nucleotide gated channel subunit alpha 1)
Canis lupus familiaris (dog) : CNGA1 (cyclic nucleotide gated channel subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnga1 (cyclic nucleotide gated channel subunit alpha 1)
Sus scrofa (pig) : CNGA1 (cyclic nucleotide gated channel subunit alpha 1)
Chlorocebus sabaeus (African green monkey) : CNGA1 (cyclic nucleotide gated channel subunit alpha 1)
Heterocephalus glaber (naked mole-rat) : Cnga1 (cyclic nucleotide gated channel subunit alpha 1)
more info ...
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01438,155,771 - 38,171,107 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1438,155,759 - 38,171,010 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01437,966,503 - 37,981,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,017,762 - 38,033,098 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11438,021,111 - 38,036,448 (+)NCBI
Celera1434,842,269 - 34,857,640 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cnga1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621815
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.