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Gene: Cnga1 (cyclic nucleotide gated channel subunit alpha 1) Rattus norvegicus
Symbol: Cnga1
Name: cyclic nucleotide gated channel subunit alpha 1
Description: Exhibits cGMP binding activity and intracellular cGMP-activated cation channel activity. Involved in membrane depolarization; regulation of cytosolic calcium ion concentration; and spermatogenesis. Localizes to the cytoplasm; intracellular cyclic nucleotide activated cation channel complex; and terminal bouton. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel alpha 1); PARTICIPATES IN altered visual phototransduction pathway; calcium/calcium-mediated signaling pathway; retinitis pigmentosa pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: cGMP-gated cation channel alpha-1; Cncg; CNG channel alpha-1; CNG-1; CNG1; cyclic nucleotide gated channel alpha 1; cyclic nucleotide-gated cation channel; cyclic nucleotide-gated cation channel 1; cyclic nucleotide-gated channel alpha-1; cyclic nucleotide-gated channel, photoreceptor; HCN; rod photoreceptor cGMP-gated channel subunit alpha
Is Marker For: Strains:   SD  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01438,155,771 - 38,171,107 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01437,966,503 - 37,981,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41438,017,762 - 38,033,098 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11438,021,111 - 38,036,448 (+)NCBI
Celera1434,842,269 - 34,857,640 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cnga1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621815
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.