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Gene: Fen1 (flap structure-specific endonuclease 1) Rattus norvegicus
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Symbol: Fen1
Name: flap structure-specific endonuclease 1
Description: Predicted to have DNA binding activity; metal ion binding activity; and nuclease activity. Involved in memory. Localizes to the nucleus. Predicted to colocalize with the nuclear chromosome, telomeric region. Orthologous to human FEN1 (flap structure-specific endonuclease 1); PARTICIPATES IN base excision repair pathway; DNA replication pathway; non-homologous end joining pathway of double-strand break repair; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FEN-1; flap endonuclease 1; flap structure-specific endonuclease; MGC94425
Orthologs:
Homo sapiens (human) : FEN1 (flap structure-specific endonuclease 1)  HGNC  Alliance
Mus musculus (house mouse) : Fen1 (flap structure specific endonuclease 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fen1 (flap structure-specific endonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FEN1 (flap structure-specific endonuclease 1)
Canis lupus familiaris (dog) : FEN1 (flap structure-specific endonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fen1 (flap structure-specific endonuclease 1)
Sus scrofa (pig) : FEN1 (flap structure-specific endonuclease 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01226,251,516 - 226,256,160 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01233,196,200 - 233,200,756 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41212,688,118 - 212,692,486 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11212,846,547 - 212,850,916 (-)NCBI
Celera1204,341,544 - 204,345,912 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Fen1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621821
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.