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Gene: Dkk3 (dickkopf WNT signaling pathway inhibitor 3) Rattus norvegicus
Symbol: Dkk3
Name: dickkopf WNT signaling pathway inhibitor 3
CRRD ID: 621846
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in adrenal gland development; negative regulation of canonical Wnt signaling pathway; and negative regulation of cellular biosynthetic process. Predicted to localize to extracellular space. Orthologous to human DKK3 (dickkopf WNT signaling pathway inhibitor 3); INTERACTS WITH 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dickkopf 3 homolog; dickkopf 3 homolog (Xenopus laevis); dickkopf homolog 3; dickkopf homolog 3 (Xenopus laevis); dickkopf-related protein 3; p29; Reic
Homo sapiens (human) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)  HGNC  Alliance
Mus musculus (house mouse) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Canis lupus familiaris (dog) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
Sus scrofa (pig) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Chlorocebus sabaeus (African green monkey) : DKK3 (dickkopf WNT signaling pathway inhibitor 3)
Heterocephalus glaber (naked mole-rat) : Dkk3 (dickkopf WNT signaling pathway inhibitor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01176,940,424 - 176,983,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1176,940,693 - 176,983,045 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01183,919,812 - 183,962,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41169,924,617 - 169,964,692 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11170,043,564 - 170,084,626 (-)NCBI
Celera1164,115,480 - 164,157,817 (-)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Dkk3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 621846
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.